The side stick control comes to mind as a potential weakness of the airbus design… after i saw a documentary on Air France Flight 447.
Copied the below from wikipedia…
In April 2012 in The Daily Telegraph, British journalist Nick Ross published a comparison of Airbus and Boeing flight controls; unlike the control yoke used on Boeing flight decks, the Airbus side stick controls give little visual feedback and no sensory or tactile feedback to the second pilot. Ross reasoned that this might – in part – explain why the handling pilot’s fatal nose-up inputs were not countermanded by his two colleagues.
In a July 2012 CBS report, Sullenberger suggested that the design of the Airbus cockpit might have been a factor in the accident. The flight controls are not mechanically linked between the two pilot seats, and Robert, the left seat pilot who believed he had taken over control of the plane, was not aware that Bonin had continued to hold the stick back, which overrode Robert’s own control.