If you increase the temp, it becomes harder for the plane to gain speed and thus take off. You would need to plan accordingly to adjust the weight of your plane/temp outside/runways of choice if setting it high up. Conversely, if you set the temp to some cold, then you’d get much better performance.
The wind in the game will either hinder the speed, help the speed, or toy around with the flight of your plane. Depends on what heading you set the wind to blow at but if the wind is traveling in the same direction as you, then you will experience an easier time getting to speed. If you’re flying into the wind, then it’ll be harder to accelerate to speed. If you’re being hit by wind from the side (Crosswind), then the plane will be shifting in the direction the wind is blowing. You can also put wind gusts in to make things more juicy,
Turbulence will make the flight bumpy. Long story short, turbulence will toss you plane around in all directions and it could even spin you out of control. The heavier you are, the more control you have in higher turbulence levels. Plan your weight and turbulence levels accordingly.
Hope this helps.
Long live the DC-9!