Sure! The winds usually suit either 10/28 and the large amounts of traffic and terminal/taxiway layout means it’s impractical. It’s only used when the crosswind limits are exceeded and / or 28/10 is closed for maintenance.
Negative, the Sierra taxiways is barely used for aircraft taxiing to T2. The only time they would really taxi via the Sierra taxiway is when the early morning US flights arrive in. The usual taxi route is via Sierra, Whiskeys and the Foxes 👍
A very similar situation to VABB (Mumbai, India). The most used runway is 27/09, and the cross-runway as it’s called (32/14) is usually used as a taxiway unless there’s strong crosswinds or the main runway is being repaired. This is both due to prevailing winds, and the fact that 32 doesn’t have a precision approach.
In fact, Mumbai, in spite of having two runways has been deemed to be a single-runway airport, lol.