Yes, been on both an A320 and 757 full motion Level D sim.
Both were CAE sims, one at Gatwick and one at Burgess Hill in the UK. Both were a lot of fun!
The Airbus was a joy to fly, very easy and the side stick feels really natural to use.
The 757 was a very slippery plane to fly, and needed a bit more concentration to handle - but (eventually) getting a good landing was rewarding.
The thing that struck me with the big sims is the optics - it’s amazing how well they create the sense of depth, height and distance compared to the lesser fixed base trainers.
If you ever get a chance, give it a go. You can also book a group with 15 minutes per person to get the price down as the full motion sims are quite expensive.