Biggest Region?

Guys, what region can take me from one airport to another above 250nm

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Correct me if I’m wrong, but the longest route I think you can do is in Hawaii - Dillingham (PHDH) to Kaalaiki (HI25). Takes about 2 hours in a Cessna 172.
PS watch out for the Volcano on approach to Kaalaiki - it’s quite tall.

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Here am talking Boeing 777-300er
Flying at 25000ft with 450 knots will get there in 30-45 mins
But thanks😀

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Ive take the Region Amsterdam 8 months ago, fly with B77W Sky Team Air France from KHAF to same KHAF Airport and Ive need 45-50 min. around.
see pls the link ( https://drive.google.com/file/d/1yNdjSUyUWFNQ5wOSB-Ul8sAfkV3dAyc5aQ/view )

Guys, he is not talking about which takes the longest or shortest time. Just the longest distance.

@Temidayo_Ekundayo 450 knots seems awfully fast…

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Just do a couple of circuits of any region.

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For that height, 450 knots seems ok because, a lot of congested areas requires some aircraft to still cruise at fl250 at cruising speed

At that height, you should be cruising at about Mach .78

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For distances over 250nm you have KMKE-KPIA in the Chicago region, KLAX-KSAN if you depart from the runways facing to the east (map point of view) and making a half moon so as to not having to make sharp turns.

Ive make the distance/routes longer for me, thats a example from me.