It will likely be easier for everyone, pilots and ATC. The work flow for the controllers, especially approach, should be a little easier. Centre frequencies will really some in to their own too.
By it’s very nature our regions tend to squeeze 50+ pilots in to 2 or 3 airports, which are about 30 minutes away from each other, if not closer.
This doesn’t really give CTR a chance to get stuck in and space the aircraft out.
I also think we’ll see more controllers on duty, again because you can enjoy more varied traffic without draining the traffic away from local airports.
For example, KSAN / KLAX / KSFO and KSEA could all be open and each airport have a managable amount of traffic.
KBOS / KJFK / KIAD / KATL and KMIA could be a fun setup too.
At the moment if we have the socal region open, it’s 99% people flying KSAN to KLAX and the other controllers at KPSP / KVCV twiddling their thumbs a bit.